Peritumoral edema resolves infrequently in surgically treated patients with intracranial meningioma- a retrospective study of 279 meningioma patients.

ABSTRACT:

Background

The resolution of peritumoral brain edema (PTBE) following surgery for intracranial meningioma (IM) is poorly understood. We hypothesized that PTBE represents a more permanent rather than resolving parenchymal change. Therefore, our aim was to assess the frequency of PTBE resolution following gross total resection (GTR) of IM.

Methods

IM patients who were operated on in the study hospital between 2000 and 2020, who had preoperative magnetic resonance imaging (MRI) showing PTBE and a follow-up MRI performed at least one year after surgery, were retrospectively identified. To minimize confounding by PTBE related to a postoperative residual tumor, only patients who had undergone GTR were included. PTBE was defined as hyperintensity on either pre- or postoperative flu

SUBMITTER: Laajava J 

PROVIDER: S-EPMC12040978 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature