Safety of emergent carotid stenting after thrombolysis: a multicenter retrospective matched analysis.

ABSTRACT:

Purpose

Mechanical thrombectomy (MT) with emergent carotid artery stenting (eCAS) has been suggested to provide greater benefits for patients with tandem lesions (TL), but there is uncertainty about the most appropriate peri-procedural antiplatelet therapy for patients at higher risk of brain hemorrhage. This study aimed to assess the safety of intravenous thrombolysis (IVT) in patients with acute TL undergoing MT with eCAS.

Methods

The databases of 17 stroke centers were retrospectively screened for consecutive patients with acute TL who underwent MT and eCAS. Propensity score matching (PSM) was used to evaluate the safety of IVT, balancing for peri-procedural antiplatelet therapies. Primary outcome measures were the occurrence of parenchymal hemorrhage (PH) type 2 and mort

SUBMITTER: Colo F 

PROVIDER: S-EPMC12041103 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature