Cost utility analysis of antibiotics compared with operative treatment in uncomplicated acute appendicitis.
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ABSTRACT: Appendicitis is the most common acute abdominal condition affecting general surgical practice. Recently, conservative treatment with antibiotics has been considered as an alternative. Therefore, this study was conducted to evaluate if antibiotics could be cost-effective compared to laparoscopic appendectomy or open appendectomy. A prospective study was undertaken to estimate health-related quality of life for antibiotic and operative treatment, and to ascertain costs in a cohort. A societal perspective incremental cost-effectiveness ratio (ICER) at 1 year after surgery was estimated. A probabilistic sensitivity analyses was performed. ICERs were estimated comparisons between individual antibiotics, laparoscopic appendectomy, and open appendectomy in uncomplicated acute appendicitis. Antibi
SUBMITTER: Poprom N
PROVIDER: S-EPMC12041463 | biostudies-literature | 2025 Apr
REPOSITORIES: biostudies-literature
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