Silk-based microparticles for the adsorption of methylene blue: formulations, characterization, adsorption study, <i>in silico</i> molecular docking, and molecular dynamics simulation.

ABSTRACT: Although silk-derived biomaterials have garnered attention for environmental remediation due to their sustainability, biocompatibility, and biodegradability, the application of silk fibroin-based microparticles (FNP) for pollutant dye adsorption remains vastly underexplored. Hence, this study pioneers the fabrication and characterization of FNP for the removal of methylene blue (MB), offering a comprehensive comparison with two other silk-based states of raw silk cocoon pieces (SC) and sericin-degummed silk fibers (SD). Remarkably, FNP achieved an adsorption capacity of 122.98 mg g^-1, over 32-fold higher than both SC and SD (3.8 mg g^-1), highlighting its superior efficiency. The adsorption performance of FNP was strongly influenced by experimental variables including

SUBMITTER: Pham DT 

PROVIDER: S-EPMC12042079 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature