Implication of taxonomic abundance of gut microbiota in prediabetes: a systematic review.

ABSTRACT:

Background

Prediabetes is defined by blood glucose levels that are higher than normal but below the diagnostic threshold for diabetes. Environmental factors associated with diabetes may contribute to its development through alterations in the gut microbiota. Recent studies suggest that changes in the composition and function of the gut microbiota play a role in the pathogenesis of diabetes mellitus and other metabolic disorders.

Objective

This study aims to systematically examine taxonomic abundance and its implications in the gut microbiota of individuals with prediabetes, identify key dysbiotic patterns, and explore their potential role in inflammation, insulin resistance, and progression to type 2 diabetes.

Methods

We conducted a systematic literature review follow

SUBMITTER: Liberty IA 

PROVIDER: S-EPMC12042084 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature