Association of Ambient Air Pollution and Temperature Exposure with Placental Abruption: A Nested Case-Control Study Based on Live Birth Registrations.

ABSTRACT:

Background

Placental abruption, a rare disorder of unclear etiology, lacks evidence to illustrate its relationship with exposure to air pollution and temperature.

Objective

This study aimed to investigate the association between exposure to ambient pollutants and temperatures and placental abruption to identify susceptible time windows and subpopulations.

Methods

A nested case-control study was based on a live birth registration database in Chongqing, the largest Chinese municipality in China, from 2018 to 2022. The placental abruption cases were each matched with four controls by maternal age at delivery, gestational week, gravidity, parity, and delivery date. Six ambient pollutants [particulate matter (PM) with aerodynamic diameter ≤2.5μm (PM2.5), PM with aerodynami

SUBMITTER: Wang T 

PROVIDER: S-EPMC12042270 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature