Hepatitis B associated with severe COVID-19: a nationwide cohort study in Sweden.

ABSTRACT:

Purpose

Individuals with severe liver disease are more vulnerable to severe COVID-19, but the association between chronic hepatitis B virus (HBV) infection and severe COVID-19 remains unclear. This study evaluates this relationship.

Methods

We analysed nationwide Swedish data from national databases and healthcare registers, identifying laboratory-confirmed COVID-19 cases from February 2020 to April 2021. Chronic HBV infection was classified into cases with and without cirrhosis. Multivariable logistic regression assessed the association between HBV and severe COVID-19, adjusting for demographics, comorbidities, vaccination, and socioeconomic factors.

Results

Among 1,057,174 COVID-19 cases, 2,902 had chronic HBV infection, which was associated with increased risk of s

SUBMITTER: Jakobsson F 

PROVIDER: S-EPMC12042447 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature