Elevated antibiotic resistance gene abundance of ICU healthcare workers, a multicentre, cross-sectional study.

ABSTRACT:

Objective

Studies suggest that the colonization of multidrug-resistant organism in the gut of healthcare workers is similar to that of healthy individuals. However, due to exposure to medical environments, is the abundance of antibiotic resistance genes (ARG) in the gut of ICU healthcare workers higher than that of healthy individuals?

Design

Prospective, multicentre, cross-sectional study.

Setting

Eight medical centers in China, recruiting from January 2024 to February 2024.

Participants

303 Healthy people (201 ICU healthcare workers and 103 healthy controls) were screened and 290 Healthy people (191 ICU healthcare workers and 99 healthy controls) were included in analysis.

Main outcome measures

Fecal samples were collected and subjected to metagenomic

SUBMITTER: Huang L 

PROVIDER: S-EPMC12042561 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature