Synergistic impact of air pollution and artificial light at night on memory disorders: a nationwide cohort analysis.

ABSTRACT:

Background

Air pollutants and outdoor artificial light at night (ALAN) are known health risks, with established effects on respiratory and cardiovascular health. However, their impact on cognitive function, particularly neurodegenerative diseases like Alzheimer's, remains poorly understood.

Methods

Using data from the China Health and Retirement Longitudinal Study (CHARLS) and the China Family Panel Studies (CFPS), including 44,689 participants, memory impairment (Memrye) was defined by self-reported memory-related diseases. Cox regression models were applied to assess the relationship between pollutants, ALAN exposure, and Memrye. Interaction analyses evaluated the combined effects using relative excess risk due to interaction (RERI), attributable proportion (AP), and syner

SUBMITTER: Tao H 

PROVIDER: S-EPMC12042610 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature