Association between national action and trends in antibiotic resistance: an analysis of 73 countries from 2000 to 2023.

ABSTRACT: The world's governments have agreed on actions to address the challenge of antibiotic resistance. This raises the question of what level of national action is associated with improved outcomes, including both slower growth and lower levels of antibiotic resistance. Answering this question is challenged by variation in data availability and quality as well as disruptive events such as the COVID-19 pandemic. We investigate the association between level of national action and temporal trends in multiple indicators related to health system capacity, antibiotic use (ABU), absolute rates of resistance (ABR) and a Drug Resistance Index (DRI). Using the Global Database for Tracking Antimicrobial Resistance (TrACSS) to construct an index of national action, we apply cross-sectional regression acros

SUBMITTER: Sogaard Jorgensen P 

PROVIDER: S-EPMC12043137 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature