3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report.

ABSTRACT: The regenerative effect of platelet-rich plasma injection on cartilage in knee osteoarthritis remains controversial. The purpose of this study was to use our recently developed 3D-MRI evaluation system to examine in detail the changes in cartilage thickness occurring six months after platelet-rich plasma injection. This study included 21 knees from 16 patients with medial knee osteoarthritis. An autologous protein solution (APS) was injected as platelet-rich plasma, and magnetic resonance imaging scans were taken before and six months after the injection. Cartilage thickness was quantified in seven regions using SYNAPSE 3D. Based on previous studies, the measurement error was set at 0.1 mm. The proportion of knees in which cartilage thickness increased (>0.1 mm) was highest in the anterome

SUBMITTER: Sekiya I 

PROVIDER: S-EPMC12043159 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature