Clinical characteristics and prognosis of non-metastatic multiple gastrointestinal stromal tumors: a population-based study.

ABSTRACT:

Purpose

Multiple gastrointestinal stromal tumors (MGISTs) are relatively rare and may exhibit distinct clinical characteristics and prognosis compared to solitary GISTs (SGISTs). The objective of this study was to investigate the clinical features and prognosis of MGISTs.

Materials and methods

The Surveillance, Epidemiology, and End Results (SEER) database was used to identify all GIST patients diagnosed between 2010 and 2019. Multiple imputation (MI) was utilized to address missing data, while propensity score matching (PSM) was conducted to mitigate selection bias. The impact of demographic and clinical factors on overall survival (OS) was evaluated using Kaplan-Meier analyses and Cox proportional hazards models.

Results

A total of 6241 patients were included in the

SUBMITTER: Chen L 

PROVIDER: S-EPMC12043539 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature