Predicting Relapse of Depressive Episodes During Maintenance Treatment: The Canadian Biomarker Integration Network in Depression (CAN-BIND) Wellness Monitoring in Major Depressive Disorder Study: Predire la rechute d'episodes depressifs pendant le traitement d'entretien : Une etude de suivi du bien-etre dans les troubles depressifs majeurs du Reseau canadien d'integration des biomarqueurs pour la depression (CAN-BIND).

ABSTRACT: BackgroundRelapse rates in major depressive disorder (MDD) remain high even after treatment to remission. Identifying predictors of relapse is, therefore, crucial for improving maintenance strategies and preventing future episodes. Remote data collection and sensing technologies may allow for more comprehensive and longitudinal assessment of potential predictors.MethodsThe Canadian Biomarker Integration Network in Depression Wellness Monitoring for MDD (CBN-WELL) study was a prospective, multicentre observational study with an aim to identify biomarkers associated with relapse in patients on maintenance treatment for MDD. Participants had a DSM-5-TR diagnosis of MDD in remission and a Montgomery-Åsberg Depression Rating Scale (MADRS) score ≤14. Participants remained on their baseline medic

SUBMITTER: Lam RW 

PROVIDER: S-EPMC12043620 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature