Association between the systemic inflammation response index and mortality in cancer survivors based on NHANES 2001-2018.

ABSTRACT: Inflammatory responses play a critical regulatory role in the development and progression of cancer. As a novel inflammatory marker, the association between the systemic inflammation response index (SIRI) and mortality among cancer survivors remains unclear. This study aims to elucidate the relationship between the SIRI and all-cause mortality among cancer survivors in the United States. This study utilized continuous data from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018, with follow-up data available through December 31, 2019. All patients were divided into four groups based on their SIRI values. Cox proportional-hazards regression models, Kaplan-Meier survival curves, and restricted cubic splines (RCS) combined with Cox proportional hazards models were

SUBMITTER: Yang FR 

PROVIDER: S-EPMC12043841 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature