The impact of withholding and withdrawal life-sustaining treatment issues on patients with sepsis: a prospective, nationwide, multicenter cohort study.

ABSTRACT: Approximately half of the patients with sepsis require intensive care unit (ICU) management and their mortality rate remains high. The concept of withholding and withdrawal life-sustaining treatment (WWLST) issue was introduced to limit the suffering of critically ill patients. However, little is known about the characteristics and outcomes of WWLST in patients with sepsis. We conducted a nationwide cohort study of adult patients with sepsis prospectively collected from the Korean Sepsis Alliance Database of 20 tertiary referral or university-affiliated hospitals in South Korea between September 2019 and December 2021. Patients were classified according to WWLST issues and characteristics, and their prognoses were compared. Among the 11,981 patients with sepsis included in the study, 4430

SUBMITTER: Kim SY 

PROVIDER: S-EPMC12043919 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature