OCT vs Angiography for Guidance of Percutaneous Coronary Intervention of Calcified Lesions: The CALIPSO Randomized Clinical Trial.

ABSTRACT:

Importance

The use of intravascular imaging for calcified plaque characterization and preparation has been advocated over conventional methods to improve percutaneous coronary intervention (PCI) outcomes, but this approach has never been evaluated.

Objective

To determine if optical coherence tomography (OCT) is superior to angiography for calcified lesions PCI guidance.

Design, setting, and participants

The CALIPSO (Calcified Lesion Intervention Planning Steered by OCT) trial was a prospective, multicenter, open-label, randomized clinical trial that included patients with stable moderate to severe calcified coronary lesions on coronary angiography scheduled for PCI. The trial was conducted at 12 sites in France between December 2021 and June 2023, and data were analyz

SUBMITTER: Amabile N 

PROVIDER: S-EPMC12044539 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature