Incidence of post-induction hypotension following emergency rapid sequence induction with ketamine: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Rapid sequence induction (RSI) is a potentially-life saving intervention in critically ill patients. An important adverse effect of this procedure is post-induction hypotension (PIH), which is associated with worsened patient outcomes. Choice of induction agent can affect incidence of PIH, although the optimal drug has yet to be determined. Ketamine is postulated to reduce PIH incidence in emergency RSI when used instead of alternative agents.

Aims

This systematic review and meta-analysis aims to evaluate the effect on PIH incidence of inducing anaesthesia with ketamine during emergency RSI.

Methods

A systematic search was conducted to identify a sample of studies fulfilling criteria for population (emergency RSI), intervention (ketamine), comparator (any

SUBMITTER: de Mucha PV 

PROVIDER: S-EPMC12044812 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature