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Associations between neutrophil percentage-to-albumin ratio with all-cause and cause-specific mortality among US cancer survivors: evidence from NHANES 2005-2018.


ABSTRACT:

Background

The neutrophil percentage-to-albumin ratio (NPAR) had been suggested as a potential prognostic biomarker in various health outcomes. However, its association with mortality in cancer survivors remains unclear.

Methods

A total of 3,022 cancer survivors from the National Health and Nutrition Examination Survey (NHANES) 2005-2018 were linked to mortality outcomes from the National Death Index (NDI). Weighted Cox proportional hazards models was conducted to investigate the association between NPAR and all-cause, cancer and cardiovascular disease (CVD) mortality and the hazard ratio (HR) with 95% confidence interval (CI) were calculated. Restricted cubic spline (RCS) was used to clarify the non-linear association. Additionally, analyses for stratification and sensitivi

SUBMITTER: Wang M 

PROVIDER: S-EPMC12044878 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature