Uridine diphosphate glucose confers oxidative stress tolerance in microalgae.

ABSTRACT:

Background

Microalgae, as major primary producers on Earth, are constantly exposed to oxidative stresses from various natural environments. These oxidative stresses often seriously threaten the productivity and species composition of microalgae. However, how microalgae resist oxidative stress is still largely unknown.

Results

Here, we identified the carbohydrate metabolism intermediate uridine diphosphate glucose (UDPG) from the model microalga Phaeodactylum tricornutum as a positive regulator in response to oxidative stresses. Under oxidative stresses induced by hydrogen peroxide and high temperature, exogenous addition of UDPG and overexpression of the UDP-glucose pyrophosphorylase gene (UGPase), a key gene for intracellular UDPG synthesis, both increased oxidative stress

SUBMITTER: Zhang R 

PROVIDER: S-EPMC12044984 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature