Epithelioid Malignant Peripheral Nerve Sheath Tumor of the Breast with Breast Cancer in the Contralateral Breast: A Case Report.

ABSTRACT:

Introduction

Malignant peripheral nerve sheath tumors (MPNSTs) are common in the peripheral nerves of the head, neck, and limbs, with few reports of their occurrence in the breasts, and the epithelioid type is rare. Here, we aimed to report a case of an epithelioid MPNST of the breast.

Case presentation

A 76-year-old woman presented with bilateral breast masses. Pathological findings showed a 60-mm invasive ductal carcinoma (T3N0M0 stage IIB) on the right breast and an epithelioid MPNST on the left breast. After surgical resection, the patient was treated with endocrine therapy alone for right breast cancer, and no recurrence was observed 4 years after surgery.

Conclusion

Reports of MPNSTs in the breasts are rare. The pathological analysis showed atypia of spindle cel

SUBMITTER: Fukada R 

PROVIDER: S-EPMC12045607 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature