Cardiovascular magnetic resonance imaging markers of ageing: a multi-centre, cross-sectional cohort study.

ABSTRACT:

Aims

Cardiac ageing involves a series of anatomical and physiological changes contributing to a decline in overall performance. Cardiac magnetic resonance (CMR) provides comprehensive structural and functional assessment for detecting age-related cardiovascular remodelling. We aimed to develop a fully automated CMR model to predict functional heart age.

Methods and results

This international, multi-centre, retrospective observational study enrolled 191 healthy individuals with normal body mass index (BMI), free of metabolic, cardiovascular, and respiratory disease as the derivation cohort. Left atrial (LA) end-systolic volume and LA ejection fraction were selected for the final model. The model was validated on 366 patients with BMI >25 kg/m² and one or more comor

SUBMITTER: Assadi HS 

PROVIDER: S-EPMC12045662 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature