Evolutionary trajectory of undifferentiated connective tissue disease and impact of 2019 EULAR/ACR systemic lupus erythematosus classification criteria: insights from a longitudinal study.

ABSTRACT: Undifferentiated connective tissue disease (UCTD) is a condition characterized by serological evidence of autoimmunity and occurrence of clinical symptoms suggestive for systemic autoimmune diseases, yet not fulfilling specific classification/diagnostic criteria. In the present longitudinal, observational, retrospective study, we aimed at analysing the evolution of UCTD course, focussing on the impact of 2019 EULAR/ACR classification criteria for systemic lupus erythematosus (SLE). Since 2008 we consecutively collected data about UCTD patients. All subjects were evaluated every six months, to record the development of clinical and laboratory features suggestive for specific autoimmune diseases. Finally, we retrospectively applied the 2019 EULAR/ACR SLE classification criteria at the first

SUBMITTER: Ciancarella C 

PROVIDER: S-EPMC12045818 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature