Efficacy of the ABC Pathway for Integrated Care Across Phenotypes of Patients with Atrial Fibrillation: A Latent-Class Analysis Report from the mAFA-II Clinical Trial.

ABSTRACT:

Background

The mAFA-II cluster randomised trial demonstrated the efficacy of a mobile health-technology implemented 'Atrial fibrillation Better Care' (ABC) pathway (mAFA intervention) for integrated care management of patients with AF.

Objective

To evaluate the effect of mAFA intervention across phenotypes of patients with AF.

Design

We conducted a latent-class analysis (LCA) according to eight variables, including age and comorbidities.

Participants

The mAFA-II trial enrolled AF patients between June 2018 and August 2019 across 40 centres in China.

Main measures

We evaluated the interaction between the groups identified through LCA, and the effect of mAFA intervention on the risk of the primary composite outcome of all-cause death, stroke/thromboembolis

SUBMITTER: Corica B 

PROVIDER: S-EPMC12045915 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature