Parental conditions, modifiable lifestyle factors, and first trimester growth and development: a systematic review.

ABSTRACT:

Introduction

The embryonic period in human development is the foundation of lifelong and even transgenerational health. Although previously believed to be uniform, there is increasing evidence that embryonic growth is influenced by the conditions and modifiable lifestyle factors of parents in the periconception period. In ongoing pregnancies, a delay in growth in the first trimester has been associated with miscarriages, malformations, low birth weight, preterm birth, and small for gestational age at birth. This has stimulated research on factors associated with variations in human embryonic growth. However, there is still no consensus on which parental conditions and modifiable lifestyle factors affect first trimester growth and development and to what extent.

Objective and rat

SUBMITTER: Graafland N 

PROVIDER: S-EPMC12046076 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature