Compatibility of whole-genome sequencing data from Illumina and Ion Torrent technologies in genome comparison analysis of <i>Listeria monocytogenes</i>.

ABSTRACT: Whole-genome sequencing (WGS) has become the key approach for molecular surveillance of Listeria monocytogenes. Genome comparison analysis can reveal transmission routes that cannot be found with classic epidemiology. A widespread standard for use in genome comparison analysis involves data from short-read sequencing, generated on Illumina or Ion Torrent devices. To date, little is known about the compatibility of data from both platforms. This knowledge is essential when it comes to the central analysis of data, for example, in the case of outbreaks. We used WGS data from 47 L. monocytogenes isolates of the strain collection of the German National Reference Laboratory for L. monocytogenes, generated on either Illumina or Ion Torrent devices, to analyse the impa

SUBMITTER: Luth S 

PROVIDER: S-EPMC12046094 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature