Abuse of gabapentinoids in individuals with substance use disorders.

ABSTRACT: The abuse of gabapentinoids has increased rapidly, and death cases have been reported with increasing rates. This study examines the toxicological analysis data of substance abuse cases conducted after legal regulations were implemented in Türkiye. The focus will be on the medicolegal implications of gabapentinoid positivity in these cases. Urine samples collected between July 2021 and July 2022 from individuals (ages 18-45) presenting at Manisa Mental Health and Diseases Hospital with diagnosed or suspected substance use disorders were analyzed for the presence of pregabalin, gabapentin, and other accompanying substances. High-resolution liquid chromatography-mass spectrometry (Orbitrap) was employed for analysis. The analysis reports and sociodemographic data of 10,300 cases were retriev

SUBMITTER: Saglam I 

PROVIDER: S-EPMC12046110 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature