Genomic characterization of group B <i>Streptococcus</i> from Argentina: insights into prophage diversity, virulence factors and antibiotic resistance genes.

ABSTRACT: Group B Streptococcus (GBS) is a commensal bacterium that can cause severe infections in infants and adults with comorbidities. Resistance and reduced susceptibility to antibiotics are continually on the rise, and vaccines remain in development. Prophages have been reported to contribute to GBS evolution and pathogenicity. However, no studies are available to date on prophage contribution to the epidemiology of GBS isolates from humans in South America. In the context of an Argentinian multicentric study, we had previously phenotypically characterized 365 human GBS isolates from invasive disease, urinary infections and maternal colonization. These isolates had been whole-genome sequenced, and their prophage presence was bioinformatically determined. In this study, we genomically cha

SUBMITTER: Kovacec V 

PROVIDER: S-EPMC12046356 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature