Associations of intra-pancreatic fat deposition with triglyceride-rich lipoproteins and lipoprotein lipase.

ABSTRACT:

Aims

To investigate the associations of intra-pancreatic fat deposition (IPFD) with very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL) and lipoprotein lipase.

Materials and methods

A total of 174 participants underwent magnetic resonance imaging on a 3.0 Tesla scanner for the quantification of IPFD. Blood samples were collected following an 8-h fasting period. Triglyceride-rich lipoproteins were measured using the Lipoprint® system and classed as VLDL, IDL-C, IDL-B and IDL-A subfractions. Lipoprotein lipase was measured using ELISA. Univariable and multivariable linear regression analyses were conducted.

Results

Both IPFD and lipoprotein lipase were significantly associated with the levels of IDL-B in the most adjusted model. Specifically, eac

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12046451 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature