Prevalence of Metabolic-Associated Steatotic Liver Disease in Patients With Primary Aldosteronism.

ABSTRACT:

Objective

To assess the prevalence of metabolic associated steatotic liver disease (MASLD) in patients with primary aldosteronism (PA) compared to benign adrenal adenomas, and to evaluate the impact of hormonal excess in inducing MASLD.

Design

Single-centre retrospective study.

Methods

Hepatic steatosis was assessed by liver/spleen (L/S) ratio from unenhanced abdomen computed tomography images (reference value < 1.1) in a cohort of 41 patients with PA without cortisol cosecretion, 20 unilateral (uPA) and 21 bilateral (BPA), 50 with nonfunctioning adrenal incidentalomas (NF-AI), 48 with mild autonomous cortisol secretion (MACS) and 10 with adrenal Cushing Syndrome (CS).

Results

Hepatic steatosis was increased in patients with PA at diagnosis: L/S ratio was lower

SUBMITTER: Tizianel I 

PROVIDER: S-EPMC12046541 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature