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The role of serum and urıne neopterın levels on the determınatıon of acute cholecystıtıs severıty.


ABSTRACT:

Objective

Acute cholecystitis (AC) is one of the most common causes of hospital admissions due to abdominal pain. Early diagnosis and prompt initiation of treatment positively impact morbidity and mortality in AC. The aim of our study was to determine serum and urine concentrations of additional biomarkers at different stages of the disease, beyond those currently used in acute cholecystitis severity staging, and to evaluate their potential inclusion as new staging parameters.

Methods

This study prospectively analyzed data from 63 patients diagnosed with acute cholecystitis and treated by the same surgical team in 2020. In patients with AC, WBC, CRP, and PCT values, as outlined in the TG18 guidelines, showed an increasing trend. These values are commonly used to determine di

SUBMITTER: Yavas M 

PROVIDER: S-EPMC12046923 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature