Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies <i>Arabidopsis</i> response to viral infection.

ABSTRACT: Plant viruses represent a risk to agricultural production and as only a few treatments exist, it is urgent to identify resistance mechanisms and factors. In plant immunity, plasma membrane (PM)-localized proteins play an essential role in sensing the extracellular threat presented by bacteria, fungi, or herbivores. Viruses are intracellular pathogens and as such the role of the plant PM in detection and resistance against viruses is often overlooked. We investigated the role of the partially PM-bound Calcium-dependent protein kinase 3 (CPK3) in viral infection and we discovered that it displayed a specific ability to hamper viral propagation over CPK isoforms that are involved in immune response to extracellular pathogens. More and more evidence supports that the lateral organization of PM

SUBMITTER: Jolivet MD 

PROVIDER: S-EPMC12048157 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature