Net Benefit of Anticoagulation in Subclinical Device-Detected Atrial Fibrillation.

ABSTRACT:

Importance

The role of anticoagulation for stroke prevention in patients with device-detected atrial high-rate episodes, also known as subclinical atrial fibrillation (AF), is a subject of equipoise.

Objective

To assess the net benefit of nonvitamin K antagonist oral anticoagulants (NOACs) in patients with device-detected subclinical AF.

Design, setting, and participants

Decision analytical model run with 10 000 patients with anticoagulation and 10 000 patients without anticoagulation in a clinical scenario of deciding whether to start NOACs for stroke prevention in patients with subclinical AF. A Markov decision model was conducted on October 1, 2024, to estimate net outcomes of NOACs. The patients had stroke risk and bleeding risks similar to those of patients in ra

SUBMITTER: Winsten AK 

PROVIDER: S-EPMC12048845 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature