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Blood pressure management based on infarct volume after successful endovascular thrombectomy.


ABSTRACT:

Introduction

While the efficacy of endovascular thrombectomy (EVT) in large core infarcts has been established, the influence of blood pressure (BP) management on functional outcomes based on infarct volume remains unclear.

Patients and methods

We conducted a secondary analysis of the Outcome in Patients Treated With Intra-Arterial Thrombectomy-Optimal Blood Pressure Control (OPTIMAL-BP) trial, which compared intensive (systolic BP < 140 mmHg) versus conventional (systolic BP 140-180 mmHg) BP management within the first 24 h following successful recanalization. Patients were grouped based on an infarct volume cut-off of 50 ml, assessed 24 h post-EVT. The primary efficacy outcome was functional independence (modified Rankin Scale of 0-2) at 3 months. Change of predicted proba

SUBMITTER: Jung JW 

PROVIDER: S-EPMC12049365 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature