Influence of tumour location on the survival outcomes of upper tract urothelial carcinoma treated with radical nephroureterectomy.

ABSTRACT:

Objective

To evaluate the impact of tumour location on the survival outcomes of patients with upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU).

Method

Patients with ureteral urothelial carcinoma (UUC) or renal pelvic urothelial carcinoma (RPUC) of the Clinical Research Office of the Endourology Society (CROES)-UTUC registry were analyzed. Study outcomes included overall survival (OS), cancer-specific survival (CSS), intravesical recurrence-free survival (IRFS), and progression-free survival (PFS), which were compared using Kaplan-Meier method with log-rank test. Propensity score matching (PSM) was performed to balance the differences in tumour features between the two groups.

Result

The UUC and RPUC groups consisted of 309 (41.9%) and 429

SUBMITTER: Liu K 

PROVIDER: S-EPMC12049378 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature