Sex disparities in outcome of medication-assisted therapy of opioid use disorder: Nationally representative outpatient clinic data.

ABSTRACT:

Question

The opioid epidemic causes massive morbidity, and males have substantially greater overdose mortality rates than females. It is unclear whether there are sex-related disparities at different stages in the trajectory of opioid use disorders (OUD), from large samples in the community.

Goal

To determine sex disparities in non-medical opioid use (NMOU) at the end of treatment with medications for opioid use disorder (MOUD), using national data.

Design

Observational study of outpatient MOUD programs in the "Treatment episode data set-discharges" (TEDS-D) for 2019.

Participants

Persons aged ≥ 18 in their first treatment episode, in outpatient MOUD-based therapy for heroin or other opioids (N = 10,065). The binary outcome was presence/absence of NMOU in the m

SUBMITTER: Butelman ER 

PROVIDER: S-EPMC12051136 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature