Risk of Gallstones Increases with Multiple Dimensions of Obesity Indexes: A Prospective Study Based on the UK Biobank.

ABSTRACT:

Introduction

Numerous cohort studies have consistently shown a significant link between obesity and an increased risk of gallstones. However, body mass index (BMI) alone may not fully capture the complexity of obesity. This study aimed to analyze the associations between different obesity indexes and the incidence of gallstones, using a competing risk model.

Methods

A total of 459,523 UK Biobank participants without gallstones at baseline were analyzed. Cox proportional hazards models, competing risk models, and restricted cubic spline were performed to assess the longitudinal associations between 11 obesity indexes including a body shape index (ABSI), body adiposity index (BAI), body roundness index (BRI), conicity index (ConI), cardiometabolic index (CMI), hip circumferenc

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12052360 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature