Fimsbactin Siderophores From a South African Marine Sponge Symbiont, Marinomonas sp. PE14-40.

ABSTRACT: Low iron levels in marine habitats necessitate the production of structurally diverse siderophores by many marine bacterial species for iron acquisition. Siderophores exhibit bioactivities ranging from chelation for iron reduction in hemochromatosis sufferers to antimicrobial activity either in their own right or when coupled to known antibiotics for targeted delivery or for molecular imaging. Thus, marine environments are a sought-after resource for novel siderophores that could have pharmaceutical or industrial application. The fimsbactins A-F (1-6) are mixed catechol-hydroxamate siderophores that have only been reported to be produced by Acinetobacter species with the fimsbactin biosynthetic gene clusters (BGCs) widespread among species within this genus. Here, we identified a putative

SUBMITTER: Ikegwuoha NPP 

PROVIDER: S-EPMC12053065 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature