Rumination induction task in fMRI: Effects of rumination focused cognitive behavioral therapy and stability in youth.

ABSTRACT:

Background

Rumination is implicated in the onset and maintenance of major depressive disorder (MDD). Rumination-Focused Cognitive Behavioral Therapy (RF-CBT) effectively targets rumination and may change resting-state brain connectivity and change in activation during a rumination induction task (RIT) post-intervention predicts depressive symptoms two years later. We examined brain activation changes during an RIT in adolescents with remitted MDD following RF-CBT and evaluated RIT reliability (or stability) during treatment as usual (TAU).

Method

Fifty-five adolescents ages 14-17 completed an RIT at baseline, were randomized to 10-14 sessions of RF-CBT (n = 30) or treatment as usual (n = 25) and completed an RIT at post-treatment or equivalent time delay. The RIT includes re

SUBMITTER: Westlund Schreiner M 

PROVIDER: S-EPMC12053545 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature