Frequency, intensity and duration of physical activity is associated with frailty in older adults with cardiac aging.

ABSTRACT: While cardiovascular aging and frailty are strongly associated in older adults, their mechanistic relationship and how physical activity, through its frequency, intensity, and duration, may influence their association remains unclear. A prospective community cohort of older adults without cardiovascular disease were studied cross-sectionally for cardiac structure and function via echocardiogram, dynamometer-derived handgrip strength, skeletal muscle measurements and physical activity questionnaires. Based on handgrip strength and cardiac aging, we derived four phenotypic groups:¹ Normal², Physical frailty without cardiac aging³, Cardiac aging without physical frailty, and⁴ Physical frailty and cardiac aging. Multinomial logistic regression was us

SUBMITTER: Wang LYT 

PROVIDER: S-EPMC12053682 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature