Urinary and oral microbiota in Polish women: a pilot case-control study of breast cancer.

ABSTRACT:

Introduction

The human microbiota can be a critical component in the development and progression of various diseases, including cancer. This study aims to investigate the composition of the urinary and oral microbiota in Polish breast cancer (BC) patients relative to healthy controls (HCs) and to predict relevant metabolic pathways of microbiota in studied groups.

Methods

Urine and oral samples from 48 participants, 24 BC cases and 24 HCs, randomly selected from 417 BC cases and 514 HCs, were analyzed using next-generation sequencing of bacterial 16S rRNA gene (V1-V9) and fungal ITS regions, along with bioinformatics tools to identify and compare microbial communities and predict relevant pathways of microbiota in the studied groups.

Results

BC case urine microbiota c

SUBMITTER: Marciniak A 

PROVIDER: S-EPMC12054997 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature