Implementation of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa-HF Registry).

ABSTRACT:

Aims

The last released European guidelines on the management of heart failure (HF) recommend in patients with chronic HF with reduced ejection fraction (HFrEF) a pharmacological approach based on four fundamental drugs to be rapidly implemented and then uptitrated to modify disease progression. The aim of the Optimization of Therapy in the Italian Management of Heart Failure (OPTIMA-HF) registry is to collect data on chronic HF outpatients in different settings of care. In the present analysis, we report the first analysis of the OPTIMA-HF registry, focusing on the real-life use of guideline-directed medical therapy in patients affected by HFrEF.

Methods

OPTIMA-HF is an observational, cross-sectional, multicentre, real-life Italian registry conducted in two different clinica

SUBMITTER: Paolillo S 

PROVIDER: S-EPMC12055350 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature