Feasibility and preliminary findings of a bacterial diversity study in periodontitis: a pilot investigation from the Western Cape.

ABSTRACT:

Introduction

Periodontitis is a significant health challenge caused by a complex interaction between bacterial infection, host immune response, and environmental factors, leading to tooth loss, bone loss, and potential associations with major systemic diseases and conditions. While the determinants of periodontitis have been extensively investigated in other populations, such studies are lacking in South Africa, which represents a high-risk population. Therefore, this study was conducted to characterize the subgingival bacterial biodiversity in the periodontal pockets of patients with periodontitis in a Western Cape population.

Materials & methods

Pooled subgingival plaque samples were collected from the deepest pocket/crevices of five periodontitis cases and five controls u

SUBMITTER: Kabbashi S 

PROVIDER: S-EPMC12055840 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature