The effects of stimulation waveform and carrier frequency on tolerance and motor thresholds elicited by transcutaneous spinal cord stimulation in stroke.

ABSTRACT:

Objective

With growing interest in translating transcutaneous spinal cord stimulation (tSCS) into rehabilitation for different neurologic injuries, understanding the effects of various combinations of stimulation parameters becomes essential.

Methods

Twenty-one participants post-stroke completed an assessment to determine their resting motor threshold (RMT) (minimum current required to elicit a muscle response) and tolerance levels (uncomfortable current intensity) to 12 stimulation configurations: two square waveforms, biphasic and monophasic, paired with six carrier frequencies (unmodulated: 0, and modulated: 1, 3, 5, 7, and 10 kHz).

Results

The results demonstrated that increasing carrier frequency increased participants' tolerance level and RMTs. Carrier frequency

SUBMITTER: Yang C 

PROVIDER: S-EPMC12056781 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature