Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis.

ABSTRACT:

Background

The optimal management strategy for new-onset atrial fibrillation (NOAF) in patients with sepsis remains unclear. This study aimed to investigate and compare the associations of rhythm control medications versus rate control medications with mortality outcomes in septic patients with NOAF.

Methods

This propensity score-matched cohort study utilized data from the Medical Information Mart in Intensive Care-IV database. Adult septic patients with NOAF were categorized into two groups based on initial medications (rhythm or rate control). The primary outcome was 28-day mortality, with secondary outcomes including intensive care unit(ICU),1-year mortality.

Results

A total of 586 patients were included in the prematched cohort, with 277 patients remaining after p

SUBMITTER: Weng C 

PROVIDER: S-EPMC12057229 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature