Nonlinear association between serum albumin levels and all-cause mortality in elderly patients with chronic aortic regurgitation.

ABSTRACT:

Background

Low serum albumin levels are established predictors of adverse outcomes in various cardiovascular conditions. However, the role of serum albumin in mortality among elderly patients with chronic aortic regurgitation (AR) has not been thoroughly investigated. This study aims to assess the relationship between serum albumin levels and mortality in this specific patient population.

Methods

Our analysis included 873 elderly AR patients from the China Valvular Heart Disease study, with baseline serum albumin measured at enrollment. Mortality outcomes were monitored for two years post-enrollment, employing a Cox proportional hazards model with a two-piecewise Cox proportional hazards framework to investigate the nonlinear relationship between serum albumin levels and all

SUBMITTER: Li MH 

PROVIDER: S-EPMC12060144 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature