Genetic and environmental contributions to epigenetic aging across adolescence and young adulthood.

ABSTRACT:

Background

Epigenetic aging estimators commonly track chronological and biological aging, quantifying its accumulation (i.e., epigenetic age acceleration) or speed (i.e., epigenetic aging pace). Their scores reflect a combination of inherent biological programming and the impact of environmental factors, which are suggested to vary at different life stages. The transition from adolescence to adulthood is an important period in this regard, marked by an increasing and, then, stabilizing epigenetic aging variance. Whether this pattern arises from environmental influences or genetic factors is still uncertain. This study delves into understanding the genetic and environmental contributions to variance in epigenetic aging across these developmental stages. Using twin modeling, we analy

SUBMITTER: Kuznetsov DV 

PROVIDER: S-EPMC12060359 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature