Four-dimensional flow provides incremental diagnostic value over echocardiography in aortic stenosis.

ABSTRACT:

Aims

Four-dimensional flow cardiovascular MRI (4D flow CMR) has emerged as a promising technique for assessing aortic stenosis (AS). This study aimed to evaluate the agreement between 4D flow CMR and transthoracic echocardiography (TTE) in estimating peak aortic valve (AV) velocities (V_Peak), grading AS severity and predicting AV intervention in a real-world setting.

Methods

Participants from the PREFER-CMR registry who had consecutive TTE and 4D flow CMR were included. AS severity was graded using established protocols using three echocardiographic parameters (V_Peak, AV area and mean pressure gradient) and CMR-derived V_Peak.

Results

The study recruited 30 patients (mean age 75.4 years, 67% male), with 17 undergoing AV intervention. Co

SUBMITTER: Grafton-Clarke C 

PROVIDER: S-EPMC12060880 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature