The Impact of Beta-Blocker Maintenance on Decompensated Heart Failure: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Acute Heart Failure (HF) is related to a significant hospital mortality rate and functional impairment in many patients. However, there is still a lack of studies that support the use of Beta-blockers (BB) in the management of decompensated HF.

Objective

This study aimed to evaluate the impact on mortality of maintaining BB in patients with decompensated HF.

Methods

A systematic review and meta-analysis was performed, using the databases PubMed, Cochrane Library, SCIELO and BVS, selecting only cohort studies and Randomized Clinical Trials (RCTs) from the last 10 years, which have been selected based on inclusion and exclusion criteria.

Results

An 86% reduction in the risk of in-hospital death was found (RR=0.14, 95% CI: 0.10- 0.18) in patients with H

SUBMITTER: da Silva Neto LFL 

PROVIDER: S-EPMC12060926 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature