Multivariate Profiling of Physical Resilience in Older Adults After Total Knee Replacement Surgery: Results From a Prospective Observational Study.

ABSTRACT:

Background

As individuals age, their ability to cope with and recover from health challenges becomes vital for maintaining independence and quality of life. This study aims to develop a multivariate phenotype of physical resilience based on individual recovery dynamics before and after a physical stressor.

Methods

This prospective observational study included 104 individuals aged ≥60 who underwent elective total knee replacement (TKR) for degenerative joint disease between December 2, 2019 and January 4, 2023. A multivariate resilience phenotype was derived from physical function assessments over 12 months after TKR using the Short Physical Performance Battery, the Pittsburgh Fatigability Scale Physical Subscale, the Knee Injury and Osteoarthritis Outcome Quality of Life Sco

SUBMITTER: Xue QL 

PROVIDER: S-EPMC12061853 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature