Isolation and characterization of a novel lytic bacteriophage Pv27 with biocontrol potential against <i>Vibrio parahaemolyticus</i> infections in shrimp.

ABSTRACT:

Background

Vibrio parahaemolyticus is a major disease-causing species of Vibrio that is pathogenic to both farmed shrimp and humans. With the increasing spread of antibiotic-resistant V. parahaemolyticus strains, bacteriophages (or phages) are considered potential agents for biocontrol as an alternative to antibiotics. In this study, a bacteriophage capable of lysing V. parahaemolyticus, named Pv27, was isolated, characterized, and evaluated for its potential to control Vibrio infections as a natural therapy.

Methods

Phage Pv27 was isolated using the double-layer agar technique and its morphology was characterized by transmission electron microscopy (TEM). We further assessed the host range specificity, optimal multiplicity of infection (MO

SUBMITTER: Hien VT 

PROVIDER: S-EPMC12063606 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature